We identified 31 meta-analyses that examined performance across relevant tasks among 30 different clinical populations. The results suggest that social cognitive deficits appear to be a core cognitive phenotype of many clinical conditions.
We identified 31 meta-analyses that examined performance across relevant tasks among 30 different clinical populations. The results suggest that social cognitive deficits appear to be a core cognitive phenotype of many clinical conditions.
Major depressive disorder affects hundreds of millions of people, is among the leading causes of disability worldwide. While a range of effective drugs are available, the majority of patients do not achieve symptomatic remission. Precision psychiatry offers a range of exciting possibilities for optimizing effective prevention, diagnosis, and treatment of psychiatric disorders.
The origins and rationale of the Cambridge Neuropsychological Test Automated Battery (CANTAB) as a cross-species translational instrument suitable for use in human neuropsychopharmacological studies are reviewed.
Cognitive dysfunction in schizophrenia is an important target for novel therapies. Computerised cognitive assessment may optimise the statistical power of cognitive trials by reducing measurement error and between-site variability and decreasing patient attrition through increased tolerability.
