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Latent inhibition and its potential as a biomarker for schizophrenia

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Postoperative cognitive dysfunction: an acute approach for the development of novel treatments for neuroinflammation

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Assessing cognitive function in clinical trials of schizophrenia

Cognitive dysfunction in schizophrenia is an important target for novel therapies. Computerised cognitive assessment may optimise the statistical power of cognitive trials by reducing measurement error and between-site variability and decreasing patient attrition through increased tolerability.

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The Use of Cognitive Screening in Pharmacotherapy Trials for Cognitive Impairment Associated With Schizophrenia

The Use of Cognitive Screening in Pharmacotherapy Trials for Cognitive Impairment Associated With Schizophrenia

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Effects of 7.5% Carbon Dioxide and Nicotine Administration on Latent Inhibition

Here, two complementary experimental studies suggest latent inhibition is modified by manipulations that are relevant to the detection and treatment of schizophrenia. These results suggest that this latent inhibition task merits further investigation in the context of neurobiological sub-groups suitable for novel treatment strategies.

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